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doi:10.3389/fphar.2021.786596

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Sequencing of colonic microorganisms revealed that EGCG dramatically modulated the architecture of the rat intestinal microbial communities, with a marked percentage gain in the proportion of beneficial flora, and that two intestinal microorganisms, Christensenellales and Oscillospirales, are known to be probiotic, whereas other microorganisms had significantly increased abundance in the treated group but there is not yet enough information to indicate that they are probiotics

Serum LC (per unit increment) significantly lowered the risk of overall cancer (OR = 0.86, 95% CI: 0.79 to 0.94), digestive system cancer (OR = 0.82, 95% CI: 0.69 to 0.97), and non-digestive system cancer (OR = 0.87, 95% CI: 0.78 to 0.98) in the multivariate analysis

The other subset of cases has a slower, more gradual onset of symptoms, including the presence of macrophages with nuclear debris (ingested lens material)