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Why HbA1c May Be Unreliable in B12 Deficiency B12 deficiency alters red cell turnover and erythropoiesis, making HbA1c potentially unreliable in either direction the distortion is variable and cannot be predicted

The correct technique is to let the water flow gently down the side of the vial, allowing the powder to dissolve passively.

Martinez-Outschoorn UE, Lin Z, Trimmer C, Flomenberg N, Wang C, Pavlides S et al

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Mitochondrial involvement in IGF-1 induced protection of cardiomyocytes against hypoxia/reoxygenation injury
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