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In most of the studies analyzed, the efficacy of the peptide was dose-dependent

doi: 10.1016/j.parint.2020.102160 29 OlszewskiK

It is a crucial component of any health regimen aimed at supporting the detoxification processes and overall well-being of our canine companions

Moreover, a subchronic toxicity study conducted on Wistar rats for a duration of 13 weeks reported no observed adverse effect level (NOAEL) of 500 mg/kg body weight [66]

In addition, it is further emphasized to conduct large sample sized studies to determine the potential hazards, side effects, and influence on metabolic health associated with long-term PQQ administration

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