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While HSC-initiated trained immunity is essential to form long-term memory to launch more robust immune response at young age, this protective mechanism comes at a cost during the aging process when HSCs are exposed to repeated cellular damage and insults

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Cell 152 , 504518 (2013)

No trials engaged in a systematic comparison of exclusive morning vs

Whats not solid, at least not yet, is the human side of the equation, its still mostly a blank page
