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Your provider will monitor you to make sure youre not experiencing any allergic reactions or adverse side effects during your treatment

The production of GPX4 and other selenoproteins is highly dependent on SEPHS2, and SEPHS2 has been shown to be a potential target for cancer therapy because of its important role in cancer cell survival

89Zirconium-labelled girentuximab deferoxamine (89Zr-DFO-girentuximab) is on another clinical trial (NCT05563272)

In GBM, this reaction has effects beyond metabolism: -KG acts as a cofactor for KDM6A, a histone demethylase that removes H3K27me3, a repressive epigenetic molecule