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65,66,67 MTHFD2 is postulated to be the main switch that produces additional one-carbon units in mitochondria to enable rapid growth
doi:10.1081/clt-200068842

Three of these metabolites, shikimate, 3-dehydroquinate and O5(1-carboxyvinyl)-3-phosphoshikimate, are intermediates of the shikimate pathway (Supplementary Fig

Accordingly, restricting exogenous thiols provides a safer alternative for mobilizing cellular defense programs

[DOI] [PubMed] [Google Scholar] 28.Chang C-H, Tsai W-C, Lin M-S, Hsu Y-H, Pang J-HS

Therapeutic implications for overcoming radiation resistance in cancer therapy
