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however, this is controversial in vivo (189)

This explains why topical applications achieve far lower tissue concentrations than injection

When NNMT activity is high, NAD+ is depleted, metabolic rate slows, and fat accumulation increases

[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Sanz-Cuesta T., Escortell-Mayor E., Cura-Gonzalez I., Martin-Fernandez J., Riesgo-Fuertes R., Garrido-Elustondo S., Mario-Surez J.E., lvarez-Villalba M., Gmez-Gascn T., Gonzlez-Garca I., et al

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For external use only