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doi: 10.1042/BJ20100581

Second, fetal sheep were infused with oIGF-1 for 2 hours, during which serial muscle biopsies were obtained from biceps femoris (BF) muscle to measure molecular signaling responses to oIGF-1

Different experimental outcomes were obtained due to differences in exercise (high and lowmoderate) intensity, amount of l-C provided, method, and timing of administration relative to the exercise (acute and chronic)

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Finally, while sulforaphane is generally well-tolerated at low dose, clinical trials as higher sulforaphane doses can have unwanted side effects, such as lethargy, hypothermia, and gastrointestinal distress, although these generally occur at very high doses (Yagishita et al., 2019)