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Furthermore, AS-Exos could reduce oxidative stress and neuronal death by triggering Nrf2/HO-1 signaling in TBI patients hippocampi (Salman et al., 2020

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TGF--induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation

Moreover, it is intrinsically linked to the metabolism of endogenous (12, 13)

Longer-acting hydration by hypertonic salt aerosols is possible by using divalent salts, as divalent cations are cleared by a paracellular route more slowly than sodium, which transports across the apical epithelial membrane

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