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Mechanistically, HIF-1 directly bound to the promoter of the ACSL4 gene and regulated ACSL4 transcription (Fig

The company subsequently reoriented its business model toward TGA classification as a supplementary substance , and in parallel licensed the molecule for the osteoarthritis indication to other companies

10.1074/jbc.M111.230078 62 OakleyA

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Efficacy and safety of telaglenastat plus cabozantinib vs placebo plus cabozantinib in patients with advanced renal cell carcinoma: The CANTATA randomized clinical trial