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Thiopurines in the Treatment of Steroid-Refractory Ulcerative Colitis In the case of steroid resistance, i.e., a lack of clinical improvement during induction therapy, or steroid dependencea clinical remission during steroid therapy, but a flare during dose reduction or within 3 months of discontinuing treatmentnext-line medications are used

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Top left: VX originated from organophosphate pesticide research in the 1930s1950s and was later adapted for military applications

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If you have these symptoms, consult a doctor and get tested for B12 deficiency