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doi: 10.1038/nbt.1717

Clinical trial NCT04050670 examined tirzepatide absorption at different sites and found something interesting

At the time, we had no idea what the mechanism might bea problem still unsolved even up until just to a few years ago, but then we finally figured it out: Vitamin B12 modulates the gene expression of the skin bacteria that cause acne

The dosing ranges referenced are derived from preclinical research models and observational, non-clinical protocols

1993 Dec;128(12):1391-5
