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Studies also indicate that patients with IUGR develop OS because of placental ischemia/reperfusion injury secondary to improper spiral arteriole development

Smith R, Rizvi F, Everton E, et al

Mangiferin, a phenolic compound derived from various parts of the Mangifera indica L , including its leaves, bark, and fruit, has potent antioxidant properties and inhibits SGLT-2 [109, 110]

Ive been saying this since day one, and every new data release has only made the case stronger

doi: 10.1016/j.phymed.2024.155342 78 ZhengYSunRYangHGuTHanMYuCet al

The amygdala hyperactivation, excessive sympathetic nervous system arousal, and impaired fear extinction that characterize anxiety disorders respond to different peptide targets than the anhedonia, BDNF deficits, and hippocampal atrophy more central to depression