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Sequence-specific inhibition of small RNA function

PMID: 16879768

Not Lipglass

Individual polymorphisms in MAPT (43, 76) and GSK3B (43) have not been associated with CIPN in patients treated with taxanes or vinca alkaloids, however additive polymorphisms in MAPT and GSK3B were associated with patient and clinician reported CIPN in 454 ovarian cancer patients treated with paclitaxel and carboplatin (43)

We then employed quantitative RT-PCR (QRT-PCR) to measure the expression of all 89 of these genes in WT and nhr-49(nr2041) mutant worms

PGC-1 stimulates the expression of mitochondria-related genes, such as nuclear respiratory factors 1/2 (NRF-1 and NRF-2), transcription factors encoded by the nuclear gene that regulate cellular energy metabolism in the nucleus