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Among all participants, the use of individual vitamin B 12 supplements with a daily dose range between 100 and 5000 mcg was a significant positive predictor of milk vitamin B 12 concentration

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The appearance of a pustular/papular rash associated with high levels of Vitamin B12 is well described in the medical literature even though the exact mechanism appears to be unknown

For example, a study conducted by the University of Oxford found that individuals with higher B12 levels had better cognitive function and a lower risk of developing Alzheimers disease

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These include [6, 34, 39]: Irritation at the site of injection Fatigue Nausea Light-headedness Sweatin g Adverse effects are often attributable to low-grade peptides