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doi: 10.1053/gast.1997.v112.pm9041245

For some the benefits are outweighed by the potential side effects: elevated hematocrit levels, estrogen imbalances, and perhaps most alarmingly, shrinking testicles and decreased fertility markers

B12 levels can become low as a result of inadequate nutrition, decreased absorption of this vitamin in the intestines, stomach problems, infections or cancer
There is a further complication

Y., Wu, Y
