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Most of the reproductive benefits observed in the trials are likely indirect mediated through weight loss and metabolic improvement rather than a direct drug effect on reproductive biology

But if you stick to smaller doses, it's unlikely to cause problems, says Dr

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also, lipids and C-reactive protein levels increased by week 120, yet maintaining a significant difference with respect to patients on placebo 77

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[2] These mechanisms contribute to improved glycaemic control and, in many patients, reduced food intake and weight loss