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Studies have demonstrated that the combination of natural products and chemotherapeutic drugs can exert synergistic antitumor effects through multiple mechanisms: in addition to directly inhibiting tumor cell proliferation and inducing apoptosis, it can also overcome multidrug resistance (MDR) and reduce the toxic side effects of chemotherapy

These studies emphasized the multifaceted roles of macrophage subsets in determining the plaque inflammatory state and influencing atherosclerosis progression

Papaya: Papaya being an antioxidant, can be used for skin treatment in the form of lotions, soaps, or facial peels

Chronic inflammation marked by elevated IL-6 disrupts systemic metabolism, activating other pro-inflammatory cytokines like TNF- and IL-1, creating a feedback loop that intensifies inflammation and insulin resistance [11,12]
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Global lactylome reveals lactylation-dependent mechanisms underlying T(H)17 differentiation in experimental autoimmune uveitis
