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Thirdly, in the event that the oral bioavailability of CoQ10 cannot be improved, or that CoQ10 cannot cross the bloodbrain barrier in humans, alternative routes of administration (showing promise in experimental models) should be further developed for clinical application

doi: 10.1016/j.ekir.2020.08.001

67 ParnettiL.AbateG.BartorelliL.CucinottaD.CuzzupoliM.MaggioniM.et al
Micha, R., Wallace, S.K

AAS: Writingoriginal draft

Four patients (6.90%) were taking no ASMs, 11 patients (18.96%) were on monotherapy with one ASM, while 43 patients (74.14%) were on polytherapy of two or more ASMs
