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Trudel, M

S., Fontana, W

Cancer-associated fibroblast-specific lncrna linc01614 enhances glutamine uptake in lung adenocarcinoma

(4) An increase of endogenous S 0 levels lowers endogenous radical load, and a decrease of endogenous S 0 levels increases endogenous radical load

The latter includes compounds like piperlongumine, which selectively activates oxidative stress responses in cancer cells by interacting with proteins that regulate oxidative stress, such as CBR1, GSTP1, and their complexes, thereby inducing cancer cell death under high ROS levels 119

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