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Achieving optimal long-term glycemic control as well as reducing the risk of cardiovascular (CV), neurodegenerative diseases, and mortality continues to be a challenge for a significant portion of patients with type 2 diabetes (T2DM) and type 1 diabetes (T1DM) worldwide [8,9,10,11,12,13,14]

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Moreover, external contaminants like smoke and radiation as well as genetic diseases raise the levels of ROS