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Comparison of serum fructosamine concentrations at different time points is more useful, and it is recommended to obtain a baseline result to compare with a second result 23 weeks after a treatment change, and to focus on trends rather than absolute numbers

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Getting the dose right is critical because both under-dosing (reduced efficacy) and over-dosing (increased side effects) create problems that compound over time

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On the contrary, the continued treatment of DOX-intoxicated rats with SP or L-car implies that the ovaries have survived harm due to ovarian reserve preservation