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J Neurochem 71:25102517 [DOI] [PubMed] [Google Scholar] 110.Rossato MS, Brilli E, Ferri N, Giordano G, Tarantino G (2021) Observational study on the benefit of a nutritional supplement, supporting immune function and energy metabolism, on chronic fatigue associated with the SARS-COV-2 post-infection progress

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Wang et al., 2020)

doi: 10.1016/j.biopsych.2007.04.015

Furthermore, given the aforementioned purported mechanisms for the improving effects of L-carnitine/synbiotics on weight or metabolic parameters, it could be conceived that concomitant supplementation of L-carnitine and synbiotics may confer more pronounced impacts on these indicators, potentially through simultaneous modulation of energy homeostasis (31, 33), or attenuating systemic inflammation (56, 57), in a complementary or synergistic manner probably mediated through concurrent targeting of metabolic/inflammatory signaling pathways including CPT-Ia (31, 37), AMPK (37), or NF-B (31, 34)