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doi: 10.1210/jcem-73-5-1081 88 VeldhuisJDIranmaneshAHoKKWatersMJJohnsonMLLizarraldeG

The AAPS journal , 23 (1), 22

Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease

40 Compared with other nanoformulations, it uses biocompatible lipid materials (eg, triglycerides and fatty acids) as carriers to dissolve or encapsulate the drug in the lipid core or adsorb it on the surface of the nanoparticles, including liposomes, solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), etc., and it has good biocompatibility, complete biodegradability as well as low carrier toxicity and immunogenicity

Studies in LN have identified deficiencies in both the number and function of Treg cells (155, 156)

Meanwhile, 6 kinds of alkaloids (palmatine, columbamine, jatrorrhizine, tetrahydropalmatine, and romaine) were speculated to play significant roles in the prevention of AD progression