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Usdin TB, Mezey E, Button DC, Brownstein MJ, Bonner TI

Lancet 402 , 613626 (2023)

Because TB-500 reaches all tissues rather than concentrating at one site, the dosing strategy focuses on sustaining a systemic therapeutic level across the cycle rather than targeting a precise anatomical location

As expected, the addition of the dimeric macrocycles produced a slower migrating band compared with the band of monomeric Met, indicating that the cross-linked Met dimer was formed (Fig

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