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Description
Notably, substantial disparities in thiol concentrations have been detected between malignant and normal cells
Duration of Effects: Immediate vs
Since then, RSL3 was described as an inhibitor of GPX4 and Erastin was shown to inhibit the Xc- transport system, also called the cystine/glutamate antiporter
10.1016/j.poly.2022.115738 145 PalS.TakY
198, no
These platforms enable targeted delivery of therapeutic nucleic acids, such as GPX4 mRNA to restore antioxidant capacity or ACSL4-siRNA to reduce substrate availability for lipid peroxidation (168)
