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Evidence from molecular studies, clinical interventions, and multi-omics analyses demonstrates that nutrients, bioactive compounds, and dietary patterns can influence DNA methylation dynamics, metabolic pathways, and biological aging

Drug Metabolism and pharmacokinetics of antisense oligonucleotide therapeutics: typical profiles, evaluation approaches, and points to consider compared with small molecule drugs
Of note, CpG and CL097 but not poly:IC stimulated IL-6 secretion in this assay, while poly:IC was the most efficient stimulus in inducing IFN secretion by CD11c + DCs (Fig

Beijing China 6 (10), 11531161

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