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However, SL application increased drought tolerance in Brassica rapa by improving the antioxidant defense system that reduced ROS and MDA content ( Medicago truncatula roots, leading to a high expression of SL biosynthetic genes ( 9.2 Salicylic acid Salicylic acid (SA) is a powerful phytohormone that contributes to the production of ROS in excess (acting as a pro-oxidant) while also boosting the activity of ROS-scavenging enzymes (antioxidants) during stressful conditions ( 2 O 2 , which serves as a key signal to activate the antioxidant defense system, helping the plants to cope with abiotic stress

Moreover, probiotics produce several bioactive molecules such as short-chain fatty acids (SCFAs), vitamins, antioxidants, peptidoglycans, bacteriocins, antimicrobial substances, exopolysaccharides, biosurfactants, polysaccharides, teichoic acids, lipoproteins, glycoproteins, enzymes, amino acids, peptides, growth factors, signaling and transport molecules, and co-factors, among others [17, 95, 96]

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In the present double blind clinical investigation, the effect of the oral supplementation by a plant Superoxide dismutase extract embedded (GliSODin) or not with Gliadin was evaluated in 35 patients with AIDS ( max 250/mm3 CD4+ T lymphocytes) that did not received any anti-retroviral therapy