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They further demonstrated that SIRT1 and SIRT6 couple a switch from increased glycolysis to increased fatty acid oxidation as early inflammation transitions to late inflammation, which requires NAD + production using nicotinamide phosphoribose transferase (120)

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[DOI] [PubMed] [Google Scholar] 123.Haluska P., Menefee M., Plimack E.R., Rosenberg J., Northfelt D., LaVallee T., Shi L., Yu X.Q., Burke P., Huang J., et al