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In this systematic review, we summarize clinical trials that studied the immunomodulatory effects of IF

Specifically, the HFD condition was associated with a reduction in the expression levels of 4E-BP1, S6K1, and mTOR genes, whereas the combined interventions were found to elevate the levels of 4E-BP1, S6K1, and IGF-1, in addition to enhancing muscle fiber diameter ( n = 11, age 25 1 years), older sedentary individuals ( n = 9, age 64 2 years), and older endurance-trained males ( n = 9, age 64 2 years)