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The bilateral STNs were the targeted regions for DBS, localized through presurgical structural MRI scans, intraoperative electrophysiological recordings and observed motor symptom improvement during the surgery

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These biomarkers could guide treatment decisions, helping clinicians select the most appropriate therapies for patients based on their individual senescence profiles.259 Developing Novel Delivery Systems: The efficacy of both senolytic and senomorphic therapies may be influenced by how these agents are delivered to target tissues
10.1186/s13046-019-1413-7 13 ChenM.ChenX.HuX.DaiJ.SunJ

Novel formulations and modes of delivery of levodopa
