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The primary hyperoxalurias are associated with overproduction and excessive urinary excretion of oxalate

doi:10.1371/journal.pone.0151171

Kumagai T, Matsukawa N, Kaneko Y, Kusumi Y, Mitsumata M, Uchida K

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Where there is a longitudinal melanonychia associated with loss of nail integrity this raises concern and needs immediate assessment

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