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The PGC-1/NRF1 axis is critical for the regulation of Fundc1 expression, as evidenced by both the direct binding of NRF1 and PGC-1 to the Fundc1 promoter and the stimulation of FUNDC1 protein production by PGC-1 overexpression [230]

Different cell models, including iPSCs and 3D organoids, have been developed to describe the effects of selected LS mutations on early development

Thus, it was estimated that the lid domain may play a role in facilitating efficient substrate binding and catalysis

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Deficiency of G6PD was related to significantly elevated risks of ADHD development [odds ratio (OR) of 1.2], seeking neurologist care (OR, 1.3), and psychiatrist consultations (OR, 1.1)