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Cox AJ, West NP, Cripps AW
MRgFUS therefore represents a potentially useful adjunct platform for improving the brain delivery of biologics and other disease-modifying therapies, although further studies are needed to establish its long-term safety and clinical efficacy (Rezai et al., 2022)
A phase I/II clinical study evaluating the safety, pharmacodynamics, pharmacokinetics, and activity of foretinib in a late first-line trial reported 30 mg as the maximum dosage for foretinib in phase I
