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Dysfunction in the mitochondrial Fe-S assembly machinery leads to formation of the chemoresistant truncated VDAC1 isoform without HIF-1alpha activation
Meanwhile, insufficient extracellular methionine supply in the tumor microenvironment augments PD-1 expression through decreasing the H3K79me2 level in CD4 + T cells (123)

[DOI] [PMC free article] [PubMed] [Google Scholar] 97.Gozal D, OBrien LM

The media was then removed and the formazan crystals that formed during incubation were dissolved in 1 mL DMSO and processed for OD reading

The IGF1 signalling pathway
