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Pulmonary hypertension and right heart failure are also recognized complications of OSA

In murine models of Ang II-induced AD, Ang II stimulates neutrophils via the angiotensin receptor AT1, leading to the induction of NOX, ROS production, and adhesion of mononuclear cells to endothelial cells (149)

doi: 10.1038/s41572-019-0097-9 9 HanJWChoiDLeeMYHuhYHYoonYS

To prevent or reverse the harmful effects of OS, leading to oxidative changes in the erythrocyte constituents, RBCs are equipped with a powerful antioxidant system that is able to protect not only themselves, but also other cells and tissues while circulating throughout the vascular network

[DOI] [PubMed] [Google Scholar] 62.Pai M.H., Shih Y.M., Shih J.M., Yeh C.L

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