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Methods The healing rate of gastrocutaneous fistula in rat (2-mm-diameter stomach defect, 3-mm-diameter skin defect) validates macro/microscopically and biomechanically a direct skin wound/stomach ulcer relation, and identifies a potential therapy consisting of: (i) stable gastric pentadecapeptide BPC 157 [in drinking water (10 g/kg) (12 ml/rat/day) or intraperitoneally (10 g/kg, 10 ng/kg, 10 pg/kg)], (ii) atropine (10 mg/kg), ranitidine (50 mg/kg), and omeprazole (50 mg/kg), (iii) 6-alpha-methylprednisolone (1 mg/kg) [intraperitoneally, once daily, first application at 30 min following surgery

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Brain insulin resistance in Alzheimers disease and related disorders: Mechanisms and therapeutic approaches

All patients will be informed that they can abandon the study at any time without this affecting their future medical treatment in any way

How to interpret the labs Topical and systemic exposure contexts should not be treated the same