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Vermeire S, Peeters M, et al

PRCA is a syndrome characterized by anemia, usually severe, very low reticulocyte count and complete absence of erythroid precursors on bone marrow examination

These side effects are completely normal and typically resolve within a few days to a week

In vitro studies revealed that cuezerene exhibited antiproliferative effects with an IC 50 value of 47.0 M over 72 h, causing G2/M phase cell cycle arrest and triggering programmed cell death in SPC-A1 human lung adenocarcinoma cells

Meanwhile, by decreasing the vulnerability of cells to ferroptosis through the inhibition of STING or MFN1/2, erasin's tumor-suppressive effects were reduced (Li et al., 2021a)

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