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Using electroencephalography (EEG) to assess dynamic brain connectivity, Barttfeld et al

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It is important to note however that the vast majority of GBM have wild-type IDH1 and still have dysregulation of HIF-1 and VEGF, indicating that this key process occurs most commonly via mechanisms other than those involving the presence of 2-HG

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Similarly, treatment with gamma-glutamylcysteine ethyl ester reduced indices of oxidative and nitrosative stress and preserved blood-brain-barrier (BBB) function when given immediately post-TBI (Reed et al., 2009