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*Correspondence: Takashi Tsuboi [email protected] This article was submitted to Neuroendocrine Science, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

MTHFR and Adrenal Fatigue Adrenal Fatigue represents the neuroendocrine deregulation of the body under excessive physical and emotional stress

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Kopelman takes a conservative approach, starting with less product and adding more at a follow-up if necessary

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doi: 10.1016/j.bcp.2008.02.026