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ALS pathology involves degeneration of upper and lower motor neurons, misfolded protein accumulation (e.g., TDP-43), mitochondrial dysfunction, oxidative stress, neuroinflammation, and excitotoxicity [100]

Phosphate derivatives occur in the backbone of nucleic acids, in membrane phospholipids, and as post-translational modifications of proteins

Upon photo-oxidation, with the emergence of 2 NP , the size distribution became much narrower, culminating in a single peak with a hydrodynamic diameter around 192 28 nm (Fig

The goal is to reduce swelling and discomfort and promote tissue healing

doi: 10.1007/s11427-011-4138-1