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Fxr2 in adipocytes derived from stem cell-derived exosomes (ADSC-Exos) regulate the expression of ATF3/SLC7A11, effectively reducing the susceptibility of M2 microglia to ferroptosis

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The results of a transcriptomic analysis obtained from a mouse model also revealed that the stimulation of GLP-1 receptor by high doses of exendin-4 upregulates IGF-1R typically in pancreatic islets, thus reinforcing the concept that activating the IGF-1R/IRS-2/Akt pathway mediates the prevention of -cell loss under the control of incretins (40)

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10.1016/j.repbio.2013.01.174 48

Impact of glycemic control strategies on the progression of diabetic peripheral neuropathy in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Cohort