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Glutathionylation is the most recently identified PTM that regulates the phase separation of ALS-associated RBPs

The microarray data were deposited in the GEO (Gene Expression Omnibus) database with the accession number GSE164941

The mechanism by which lactate alters the SUMOylation of APC4, as well as other cell cycle regulatory components, is by forming a complex with Zn 2+ in the active site of the SUMO protease, SENP1

Discussion Novel SAM methyltransferase RIPS-1 is involved in methionine-dependent sensitivity to thiol-reducing agent toxicity Following several large-scale forward genetic screens in C

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Ive talked to patients and providers that are quite passionate on both sides of this issue