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When compared to the results reported by Pak et al., we identified 2.2 times more peptides than their sample-specific library approach (14,600 peptides) and 1.4 times more peptides than their multi-HLA BigLib library or the Prosit-predicted library approaches (22,532 peptides) 21

Abbreviation definitions: BSO (buthionine sulfoximine, a known inhibitor of glutathione synthesis), WPI (whey protein isolate), and NAC (N-acetyl cysteine)

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Multivariate statistical analysis was performed using MetaboAnalyst v5.0 (Xia Lab, McGill University, Montreal, Quebec, Canada

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