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glutathione therapy from prodrugs to genes A glutathione-responsive L-carnitine-modified camptothecin oral nano-prodrug for cancer Glutathione Metabolism - an overview

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glutathione therapy from prodrugs to genes A glutathione-responsive L-carnitine-modified camptothecin oral nano-prodrug for cancer Glutathione Metabolism - an overview

doi: 10.1016/j.anireprosci.2021.106805 96 MaJYuanHZhangJSunXYiLLiWet al

glutathione therapy from prodrugs to genes A glutathione-responsive L-carnitine-modified camptothecin oral nano-prodrug for cancer Glutathione Metabolism - an overview

doi: 10.1096/fj.201600522R 83 XieMZhangDDyckJRBLiYZhangHMorishimaMet al

glutathione therapy from prodrugs to genes A glutathione-responsive L-carnitine-modified camptothecin oral nano-prodrug for cancer Glutathione Metabolism - an overview

Furthermore, CHAC2 appears to negatively influence CHAC1-mediated GSH degradation, suggesting a direct competitive interaction (Wang et al., 2017)

glutathione therapy from prodrugs to genes A glutathione-responsive L-carnitine-modified camptothecin oral nano-prodrug for cancer Glutathione Metabolism - an overview

Importantly, persistent activation of NRF2 that is induced pharmacologically in KEAP1-NRF2-intact cancer cells also decreases NEAA synthesis and makes them rely on exogenous NEAAs (LeBoeuf et al

glutathione therapy from prodrugs to genes A glutathione-responsive L-carnitine-modified camptothecin oral nano-prodrug for cancer Glutathione Metabolism - an overview

[5] Hypoglycemia is an early risk factor for developing diabetes

glutathione therapy from prodrugs to genes A glutathione-responsive L-carnitine-modified camptothecin oral nano-prodrug for cancer Glutathione Metabolism - an overview

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