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Description
Lipid metabolism and immune response in hepatocellular carcinoma: interplay driving tumor progression

The tolerance property of human D3 dopamine receptor is determined by specific amino acid residues in the second cytoplasmic loop

Safety, Eligibility, and Evidence for Glutathione Support Oral L glutathione has poor bioavailability (515%) due to intestinal degradation

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10.1016/j.redox.2021.102021 18

Mechanistically, GLPs exert renoprotective effects by suppressing the PI3K/Akt/mTOR signaling cascade, promoting autophagicevidenced by increased Beclin-1 expression and LC3-II/LC3-I ratio, along with decreased p62 accumulationwhile simultaneously attenuating apoptotic activity (reducing caspase-3 and caspase-9 levels) and dampening pro-inflammatory responses (lowering IL-6, IL-1, and TNF-)