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Its pathophysiology and clinical presentation are shaped by a diverse range of risk factors, which can be broadly categorized into intrinsic and extrinsic domains

[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Gai Z., Wang T., Visentin M., Kullak-Ublick G.A., Fu X., Wang Z

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However, TGF- signaling can suppress AhR expression via methyl-CpG-binding domain 2 (MBD2) -mediated promoter methylation, potentially limiting the antifibrotic efficacy of Kyn [117]
