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In humans, cyanocobalamin must undergo intracellular enzymatic conversion to the active coenzyme formsmethylcobalamin and adenosylcobalaminwhich, depending on the pH environment, can interconvert with hydroxocobalamin (Obeid et al., 2015)

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By using 5-Amino-1MQ to inhibit this enzyme, scientists were able to rejuvenate these cells in elderly mice