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Both have been identified as being abnormal in some people with ME/CFS

While outright deficiency is rare, especially in healthy individuals who consume a varied diet, certain signs can indicate low levels of L-Carnitine, such as muscle weakness, fatigue, or difficulty in achieving peak physical performance

[18] AMP IMP Inosine Hypoxanthine Xanthine Uric acid Hyperammonemia is also seen post-exercise in McArdle disease (GSD-V) and phosphoglucomutase deficiency (PGM1-CDG, formerly GSD-XIV), due to the purine nucleotide cycle running when the ATP reservoir is low due to the glycolytic block

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