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5 The disappearance of lentigines after imatinib therapy suggests a role for c-kit, a receptor tyrosine kinase that is involved in intracellular signaling, in some cases
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However, since individual patients might simultaneously be affected by pain and functional impairment, combination therapies are feasible

Uveal metastases typically emanate from primary cancer of the breast (37%), lung (27%), kidney (4%), gastrointestinal tract (4%), cutaneous melanoma (2%), lung carcinoid (2%), prostate (2%), thyroid (1%), pancreas (1%), and other sites (3%)

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Zhong P, Peng J, Hu Y, Zhang J, Shen C
